Article
The Cohesive Metastasis Phenotype in Human Prostate Cancer.
Biochimica et biophysica acta - 1 Dec 2016
Harryman William L, Hinton James P, Rubenstein Cynthia P, Singh Parminder, Nagle Raymond B, Parker Sarah J, Knudsen Beatrice S, Cress Anne E
Abstract excerpt
A critical barrier for the successful prevention and treatment of recurrent prostate cancer is detection and eradication of metastatic and therapy-resistant disease. Despite the fall in diagnoses and mortality, the reported incidence of metastatic disease has increased 72% since 2004. Prostate cancer arises in cohesive groups as intraepithelial neoplasia, migrates through muscle and leaves the gland via...
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