Article
The emergence of letermovir and maribavir drug-resistant mutations: from clinical trials to real-world studies.
Current opinion in infectious diseases - 1 Dec 2024
Zhu Violet Z, Horton Miles B, Haeusler Gabrielle M, Yong Michelle K
Abstract excerpt
PURPOSE OF REVIEW: Cytomegalovirus (CMV) infection is associated with severe clinical disease and high morbidity in immunocompromised hosts. Letermovir and maribavir, are two recently developed antiviral drugs used in the prevention and treatment of resistant and refractory CMV. Following the publication of landmark randomized trials and increased use, both clinical trial data and real-world experience has...
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