Article
Exome Variant Analysis of Chronic Periodontitis in 2 Large Cohort Studies.
Journal of dental research - 1 Jan 2017
Kasbohm E, Holtfreter B, Völker U, Petersmann A, Samietz S, Biffar R, Völzke H, Meisel P, Kacprowski T, Homuth G, Kocher T, Teumer A
Abstract excerpt
Periodontitis is characterized by inflammation of the gingival tissue. The main risk factors are socioeconomic factors, sex, age, smoking, and diabetes, but periodontal disease has also a genetic background. Previous genome-wide association studies failed to reveal genome-wide significant associations of single common single-nucleotide polymorphisms with chronic periodontitis. Using the Illumina ExomeChip data of...
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