Article
Genome wide association scan for chronic periodontitis implicates novel locus.
BMC oral health - 9 Jul 2014
Feng Ping, Wang Xiaojing, Casado Priscila L, Küchler Erika C, Deeley Kathleen, Noel Jacqueline, Kimm Hyongsup, Kim Ji-Hye, Haas Alex N, Quinelato Valquiria, Bonato Leticia L, Granjeiro Jose M, Susin Cristiano, Vieira Alexandre R
Abstract excerpt
BACKGROUND: There is evidence for a genetic contribution to chronic periodontitis. In this study, we conducted a genome wide association study among 866 participants of the University of Pittsburgh Dental Registry and DNA Repository, whose periodontal diagnosis ranged from healthy (N = 767) to severe chronic periodontitis (N = 99). METHODS: Genotypingi of over half-million single nucleotide polymorphisms was...
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