DNA methylation and histone modifications as epigenetic regulation in prostate cancer (Review).

Abstract excerpt

Prostate cancer is the second most commonly diagnosed cancer in men in Poland after lung cancer and the third leading cause of cancer-related mortality after lung and colon cancer. The etiology of most cases of prostate cancer are not fully known, and therefore it is essential to search for the molecular basis of prostate cancer and markers for the early diagnosis of this type of cancer. Epigenetics deals with...

Topics

• Chromatin Assembly and Disassembly
• DNA Methylation
• Epigenesis, Genetic
• Gene Expression Regulation, Neoplastic
• Gene Regulatory Networks
• Genetic Predisposition to Disease
• Histone Code
• Histones
• Humans
• Male
• MicroRNAs