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Fosfomycin resistance inAcinetobacter baumanniiis mediated by efflux through a major facilitator superfamily (MFS) transporter—AbaF

20 Sept 2016

Abstract excerpt

OBJECTIVES: To decipher the function of A1S_1331, named AbaF (Acinetobacter baumannii Fosfomycin efflux), one of the primary targets of AbsR25, a small RNA of A. baumannii. METHODS: abaF was cloned in a multicopy plasmid and expressed from its native promoter in an efflux-deficient strain-Escherichia coli KAM32. Drug susceptibility, accumulation and efflux of ethidium bromide (EtBr) were determined in this...

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PMID: 27650185
DOI: 10.1093/jac/dkw382

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