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Genomic and phenotypic analysis of multidrug-resistant Acinetobacter baumannii focusing on efflux pump activity and biofilm-associated genes.

Molecular biology reports - 17 Apr 2026

Gowrinathan Sivaranjani, Gururajan Gayathri, Kaliyaperumal Kathireshan A, Renganathan Senthil

Abstract excerpt

BACKGROUND: Acinetobacter baumannii evolved as a critical pathogen of global concern due to its persistence and pathogenicity. To elucidate the underlying resistance mechanism, the role of efflux pumps and biofilm-associated genes was investigated. Furthermore, the genes that serve as potential targets or biomarkers were identified, offering valuable insights for the development of novel antimicrobial agents and...

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PMID: 41995900
DOI: 10.1007/s11033-026-11791-1

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