Article
Bacteroides fragilis BmeABC efflux systems additively confer intrinsic antimicrobial resistance.
The Journal of antimicrobial chemotherapy - 1 Jul 2006
Pumbwe Lilian, Ueda Ohmi, Yoshimura Fuminobu, Chang Abraham, Smith Rachel L, Wexler Hannah M
Abstract excerpt
OBJECTIVES: To determine the prevalence of expression and function(s) of Bacteroides fragilis RND family efflux transport systems (bmeABC1-16). METHODS: The mRNA transcripts of bmeB efflux pump genes were detected in a wild-type strain ADB77 by RT-PCR and expression in different strains was quantified by comparative quantitative real-time RT-PCR. In order to determine independent or additive functions, BmeB 1, 3,...
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