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SnpFilt: A pipeline for reference-free assembly-based identification of SNPs in bacterial genomes.

Computational biology and chemistry - 1 Dec 2016

Chan Carmen H S, Octavia Sophie, Sintchenko Vitali, Lan Ruiting

Abstract excerpt

De novo assembly of bacterial genomes from next-generation sequencing (NGS) data allows a reference-free discovery of single nucleotide polymorphisms (SNP). However, substantial rates of errors in genomes assembled by this approach remain a major barrier for the reference-free analysis of genome variations in medically important bacteria. The aim of this report was to improve the quality of SNP identification in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27647159
DOI: 10.1016/j.compbiolchem.2016.09.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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