Article
Cerebrospinal Fluid Stanniocalcin-1 as a Biomarker for Alzheimer's Disease and Other Neurodegenerative Disorders.
Neuromolecular medicine - 1 Mar 2017
Shahim Pashtun, Blennow Kaj, Johansson Per, Svensson Johan, Lista Simone, Hampel Harald, Andersson Leif Christer, Zetterberg Henrik
Abstract excerpt
Stanniocalcin-1 (STC-1) is a nerve cell-enriched protein involved in intracellular calcium homeostasis regulation. Changes in calcium regulation are hypothesized to play a role in the pathophysiology of Alzheimer's disease (AD). The expression of STC-1 increases in response to ischemic stroke, but whether it is altered in neurodegenerative disorder, particularly Alzheimer's disease (AD), has not been investigated...
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