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Article

Cerebrospinal Fluid Biomarkers for Alzheimer’s Disease: The Present and the Future

1 Jan 2011

Abstract excerpt

Alzheimer's disease (AD) is the major cause of dementia in the elderly. The biochemical changes that precede AD may be present up to 20 years before the clinical manifestation of the disease. The translational development of AD biomarkers may be theoretically achieved via two different strategies: the first strategy can be defined as 'knowledge-based' (deductive method), while the second one is a...

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PMID: 21709402
DOI: 10.1159/000327756

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