Article
Cerebrospinal Fluid Amyloid Beta and Tau Concentrations Are Not Modulated by 16 Weeks of Moderate- to High-Intensity Physical Exercise in Patients with Alzheimer Disease.
Dementia and geriatric cognitive disorders - 1 Jan 2016
Steen Jensen Camilla, Portelius Erik, Siersma Volkert, Høgh Peter, Wermuth Lene, Blennow Kaj, Zetterberg Henrik, Waldemar Gunhild, Gregers Hasselbalch Steen, Hviid Simonsen Anja
Abstract excerpt
BACKGROUND: Physical exercise may have some effect on cognition in patients with Alzheimer disease (AD). However, the underlying biochemical effects are unclear. Animal studies have shown that amyloid beta (Aβ), one of the pathological hallmarks of AD, can be altered with high levels of physical activity. AIM: The objective of this study was to elucidate the effect of 16 weeks of moderate- to high-intensity...
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