Article
Longitudinal associations between exercise and biomarkers in autosomal dominant Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Nov 2024
Sewell Kelsey R, Doecke James D, Xiong Chengjie, Benzinger Tammie, Masters Colin L, Laske Christoph, Jucker Mathias, Lopera Francisco, Gordon Brian A, Llibre-Guerra Jorge, Levin Johannes, Huey Edward D, Hassenstab Jason, Schofield Peter R, Day Gregory S, Fox Nick C, Chhatwal Jasmeer, Ibanez Laura, Roh Jee Hoon, Perrin Richard, Lee Jae-Hong, Allegri Ricardo F, Supnet-Bell Charlene, Berman Sarah B, Daniels Alisha, Noble James, Martins Ralph N, Rainey-Smith Stephanie, Peiffer Jeremiah, Gardener Samantha L, Bateman Randall J, Morris John C, McDade Eric, Erickson Kirk I, Sohrabi Hamid R, Brown Belinda M
Abstract excerpt
INTRODUCTION: We investigated longitudinal associations between self-reported exercise and Alzheimer's disease (AD)-related biomarkers in individuals with autosomal dominant AD (ADAD) mutations. METHODS: Participants were 308 ADAD mutation carriers aged 39.7 ± 10.8 years from the Dominantly Inherited Alzheimer's Network. Weekly exercise volume was measured via questionnaire and associations with brain volume...
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