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Article

Turning the fate of reprogramming cells from retinal disorder to regeneration by Pax6 in newts.

Scientific reports - 19 Sept 2016

Casco-Robles Martin Miguel, Islam Md Rafiqul, Inami Wataru, Tanaka Hibiki Vincent, Kunahong Ailidana, Yasumuro Hirofumi, Hanzawa Shiori, Casco-Robles Roman Martin, Toyama Fubito, Maruo Fumiaki, Chiba Chikafumi

Abstract excerpt

The newt, a urodele amphibian, has an outstanding ability- even as an adult -to regenerate a functional retina through reprogramming and proliferation of the retinal pigment epithelium (RPE) cells, even though the neural retina is completely removed from the eye by surgery. It remains unknown how the newt invented such a superior mechanism. Here we show that disability of RPE cells to regenerate the retina brings...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 27640672
DOI: 10.1038/srep33761
PMCID: PMC5027390

Genes

RPE
PVR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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