Article
Genetic variations in TCF7L2 influence therapeutic response to sulfonylureas in Indian diabetics.
Diabetes research and clinical practice - 1 Nov 2016
Dhawan Dipali, Padh Harish
Abstract excerpt
Sulfonylureas are widely used to treat type 2 diabetes, with considerable inter-individual variation in the hypoglycaemic response to sulfonylureas. Genetic variants in the gene encoding for transcription factor-7-like 2 (TCF7L2) have been associated with type 2 diabetes. This study aimed to study the effect of variations in TCF7L2 on therapeutic response to sulfonylureas in Type 2 diabetes mellitus patients. The...
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