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Article

miR-34a Inhibits Lung Fibrosis by Inducing Lung Fibroblast Senescence

16 Sept 2016

Abstract excerpt

Cellular senescence has been implicated in diverse pathologies. However, there is conflicting evidence regarding the role of this process in tissue fibrosis. Although dysregulation of microRNAs is a key mechanism in the pathogenesis of lung fibrosis, it is unclear whether microRNAs function by regulating cellular senescence in the disease. In this study, we found that miR-34a demonstrated greater expression in...

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Share to Circular RNAs in diseases
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PMID: 27635790
DOI: 10.1165/rcmb.2016-0163oc

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