Article
The immunophenotypic fingerprint of patients with primary antibody deficiencies is partially present in their asymptomatic first-degree relatives.
Haematologica - 1 Jan 2017
Bogaert Delfien J A, De Bruyne Marieke, Debacker Veronique, Depuydt Pauline, De Preter Katleen, Bonroy Carolien, Philippé Jan, Bordon Victoria, Lambrecht Bart N, Kerre Tessa, Cerutti Andrea, Vermaelen Karim Y, Haerynck Filomeen, Dullaers Melissa
Abstract excerpt
The etiology of primary antibody deficiencies is largely unknown. Beside rare monogenic forms, the majority of cases seem to have a more complex genetic basis. Whereas common variable immunodeficiency has been investigated in depth, there are only a few reports on milder primary antibody deficiencies such as idiopathic primary hypogammaglobulinemia and IgG subclass deficiency. We performed flow cytometric...
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