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Article

Bioactivation and Regioselectivity of Pig Cytochrome P450 3A29 towards Aflatoxin B₁.

Toxins - 12 Sept 2016

Wu Jun, Chen Ruohong, Zhang Caihui, Li Kangbai, Xu Weiying, Wang Lijuan, Chen Qingmei, Mu Peiqiang, Jiang Jun, Wen Jikai, Deng Yiqun

Abstract excerpt

Due to unavoidable contaminations in feedstuff, pigs are easily exposed to aflatoxin B₁ (AFB₁) and suffer from poisoning, thus the poisoned products potentially affect human health. Heretofore, the metabolic process of AFB₁ in pigs remains to be clarified, especially the principal cytochrome P450 oxidases responsible for its activation. In this study, we cloned CYP3A29 from pig liver and expressed it in...

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Identifiers

PMID: 27626447
DOI: 10.3390/toxins8090267
PMCID: PMC5037493

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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