An integrative study identifies KCNC2 as a novel predisposing factor for childhood obesity and the risk of diabetes in the Korean population.

doi:10.1038/srep33043

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An integrative study identifies KCNC2 as a novel predisposing factor for childhood obesity and the risk of diabetes in the Korean population.

Scientific reports - 14 Sept 2016

Hwang Joo-Yeon, Lee Hyo Jung, Go Min Jin, Jang Han Byul, Park Sang Ick, Kim Bong-Jo, Lee Hye-Ja

Abstract excerpt

Obesity is a major risk factor for type 2 diabetes. To unravel the genetic determinants of obesity-associated diabetes, we performed a genome-wide study using the 1,000 Genomes-based imputation in a Korean childhood cohort (KoCAS-1, n = 484) and carried out de novo replication in an independent population (KoCAS-2, n = 1,548). A novel variant (rs10879834) with multiple diverse associations for obesity-related...

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PMID: 27623749
DOI: 10.1038/srep33043
PMCID: PMC5022012

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KCNC2

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