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Article

Identification of genetic loci enriched in obese or lean T2D cases in the Korean population.

Genes & genomics - 1 Feb 2025

Lim Eun Bi, Cho Yoon Shin

Abstract excerpt

BACKGROUND: Obesity causes many complex diseases including type 2 diabetes (T2D). Obesity increases the risk of T2D in Europeans, but there are many non-obese (lean) T2D patients in East Asia. OBJECTIVE: To discover genetic factors enriched in obese or lean T2D patients, we conducted a genome-wide association (GWA) analysis for T2D stratified by BMI in the Korean population. METHODS: In the discovery stage, 654...

Read the complete abstract on PubMed

Topics

Humans
Diabetes Mellitus, Type 2
Obesity
Genome-Wide Association Study
Male
Female
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Republic of Korea

Middle Aged

Body Mass Index

Genetic Loci

Genetic Predisposition to Disease

Adult

Thinness

Asian People

Case-Control Studies

Source

Identifiers

PMID: 39693004
DOI: 10.1007/s13258-024-01602-x

Genes

CDKAL1
PKP4

Provenance

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