Article
CCR5-Δ32 gene polymorphism is associated with retinopathy in patients with type 1 diabetes.
Molecular and cellular endocrinology - 5 Jan 2017
Słomiński Bartosz, Ławrynowicz Urszula, Myśliwska Jolanta, Ryba-Stanisławowska Monika, Skrzypkowska Maria, Brandt Agnieszka
Abstract excerpt
AIM: The aim of the study was to assess the relationship between the CCR5-Δ32 polymorphism and the risk of diabetic retinopathy (DR) in patients with DM1. METHODS: We examined 420 patients and 350 healthy controls. The analysis concerned CCR5-Δ32 polymorphism as well as levels of serum inflammatory markers (CRP, TNF-α), adhesion molecules (VCAM, ICAM-1, ICAM-3) and CCR5 ligand (MCP-1). RESULTS: We found a...
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