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Article

Variation in the Dopamine-4-Receptor Gene in Patients with Type 1 Diabetes.

Neuroendocrinology - 1 Jan 2023

Słomiński Bartosz, Skrzypkowska Maria, Myśliwiec Małgorzata, Trzonkowski Piotr

Abstract excerpt

INTRODUCTION: Because dopaminergic signaling pathways are one of the regulators of autoimmunity, we hypothesize that the -521C>T DRD4 gene polymorphism may associate with the risk of diabetes mellitus type 1 (DM1) and its comorbidities. METHODS: In this case-control study, we have examined 300 patients with DM1 in comparison to 300 healthy age-matched controls. Utilizing the amplification refractory mutation...

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Identifiers

PMID: 37080173
DOI: 10.1159/000530765
PMCID: PMC10389791

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