Article
CC-chemokine receptor CCR5-del32 mutation as a modifying pathogenetic factor in type I diabetes.
Journal of diabetes and its complications - 1 Jan 2000
Kalev Ingrid, Oselin Kersti, Pärlist Piret, Zilmer Mihkel, Rajasalu Tarvo, Podar Toomas, Mikelsaar Aavo Valdur
Abstract excerpt
The purpose of this study was to determine the CCR5-del32 allele frequency in type I (insulin-dependent) and type II (noninsulin-dependent) diabetes patients, and to test whether and how this mutation is associated with both types of diabetes. Thirty-eight type I diabetes and 111 type II diabetes patients' genotyping was performed by polymerase chain reaction assaying, and amplified products were digested with...
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