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Article

Does High Tobacco Consumption Cause Psychological Distress? A Mendelian Randomization Study.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco - 1 Jan 2017

Skov-Ettrup Lise S, Nordestgaard Børge G, Petersen Christina B, Tolstrup Janne S

Abstract excerpt

BACKGROUND: Increasing evidence suggests that smoking influences mental health negatively. This study investigated whether high tobacco consumption is causally related to psychological distress in a Mendelian randomization design, using a variant in the nicotine acetylcholine receptor gene CHRNA3-known to influence individual tobacco consumption-as instrumental variable for tobacco consumption. METHODS: Data from...

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Identifiers

PMID: 27613883
DOI: 10.1093/ntr/ntw186

Genes

CHRNA3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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