Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Iterative sorting reveals CD133+ and CD133- melanoma cells as phenotypically distinct populations.

BMC cancer - 9 Sept 2016

Grasso Carole, Anaka Matthew, Hofmann Oliver, Sompallae Ramakrishna, Broadley Kate, Hide Winston, Berridge Michael V, Cebon Jonathan, Behren Andreas, McConnell Melanie J

Abstract excerpt

BACKGROUND: The heterogeneity and tumourigenicity of metastatic melanoma is attributed to a cancer stem cell model, with CD133 considered to be a cancer stem cell marker in melanoma as well as other tumours, but its role has remained controversial. METHODS: We iteratively sorted CD133+ and CD133- cells from 3 metastatic melanoma cell lines, and observed tumourigenicity and phenotypic characteristics over 7...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to AC133 Antigen
Share to Cell Lineage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Separation

Share to Mice, Inbred NOD

Share to Mice, SCID

Share to Neoplasm Transplantation

Share to Neoplastic Stem Cells

Share to Tumor Microenvironment

Source

Open in PubMed Open full text

Identifiers

PMID: 27613604
DOI: 10.1186/s12885-016-2759-2
PMCID: PMC5017126

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Iterative sorting reveals CD133+ and CD133- melanoma cells as phenotypically distinct populations.PMID 27613604Read ↗

The Stem Cell-Associated Antigen CD133 (Prominin-1) Is a Molecular Therapeutic Target for Metastatic MelanomaSemantic proximity Read ↗

A CD24 <sup>+</sup> CD271 <sup>+</sup> Melanoma Cancer Stem Cell Possesses Hybrid Characteristics of its Single Marker Counterparts and Promotes Invasion and Therapeutic ResistanceSemantic proximity Read ↗

Cancer stem cells and human malignant melanomaSemantic proximity Read ↗

CRISPR-Cas9 Knockdown and Induced Expression of CD133 Reveal Essential Roles in Melanoma Invasion and MetastasisSemantic proximity Read ↗

Overshoot during phenotypic switching of cancer cell populations.Semantic proximity Read ↗

The Nerve Growth Factor Receptor CD271 Is Crucial to Maintain Tumorigenicity and Stem-Like Properties of Melanoma CellsSemantic proximity Read ↗

Melanoma stem cells.Semantic proximity Read ↗

Phenotypic subpopulations of metastatic colon cancer stem cells: genomic analysis.Semantic proximity Read ↗

Phenotypical and functional studies on putative cancer stem cells of human melanomaSemantic proximity Read ↗

CD133 Expression Defines a Tumor Initiating Cell Population in Primary Human Ovarian CancerSemantic proximity Read ↗

A Tumorigenic Subpopulation with Stem Cell Properties in MelanomasSemantic proximity Read ↗

Imaging and analysis of 3D tumor spheroids enriched for a cancer stem cell phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.