Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

miRNA-187-3p-Mediated Regulation of the KCNK10/TREK-2 Potassium Channel in a Rat Epilepsy Model.

ACS chemical neuroscience - 16 Nov 2016

Haenisch Sierk, von Rüden Eva-Lotta, Wahmkow Hannes, Rettenbeck Maruja L, Michler Christina, Russmann Vera, Bruckmueller Henrike, Waetzig Vicki, Cascorbi Ingolf, Potschka Heidrun

Abstract excerpt

Regulatory RNAs play a key role in the regulation of protein expression patterns in neurological diseases. Here we studied the regulation of miRNAs in a chronic rat model of temporal lobe epilepsy. The analysis was focused on a putative link with pharmacoresponsiveness as well as the functional implications of the regulation of a selected miRNA. The findings did not reveal a difference in hippocampal miRNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Resistant Epilepsy
Share to Dyrk Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electric Stimulation

Share to Epilepsy, Temporal Lobe

Share to Hep G2 Cells

Share to Phenobarbital

Share to Potassium Channels, Tandem Pore Domain

Share to Status Epilepticus

Source

Identifiers

PMID: 27609046
DOI: 10.1021/acschemneuro.6b00222

Genes

KCNK10
DYRK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

miRNA-187-3p-Mediated Regulation of the KCNK10/TREK-2 Potassium Channel in a Rat Epilepsy Model.PMID 27609046Read ↗

Systematic review and meta-analysis of differentially expressed miRNAs in experimental and human temporal lobe epilepsy.Semantic proximity Read ↗

Differential Expression Analysis of miRNAs and mRNAs in Epilepsy Uncovers Potential BiomarkersSemantic proximity Read ↗

Circulating microRNAs and isomiRs as biomarkers for the initial insult and epileptogenesis in four experimental epilepsy models: The EPITARGET studySemantic proximity Read ↗

Detection of Deregulated miRNAs in Childhood Epileptic EncephalopathiesSemantic proximity Read ↗

Circulating miRNAs expression profiling in drug-resistant epilepsy: Up-regulation of miR-301a-3p in a case of sudden unexpected deathSemantic proximity Read ↗

EpimiRBase: a comprehensive database of microRNA-epilepsy associationsSemantic proximity Read ↗

MicroRNA-335-5p suppresses voltage-gated sodium channel expression and may be a target for seizure controlSemantic proximity Read ↗

Serum MicroRNAs as Predictors of Diagnosis and Drug-resistance in Temporal Lobe Epilepsy: A Preliminary StudySemantic proximity Read ↗

The Challenge of microRNA as a Biomarker of EpilepsySemantic proximity Read ↗

GluK2 is a target for gene therapy in drug-resistant Temporal Lobe EpilepsySemantic proximity Read ↗

miRNA Dysregulation in Traumatic Brain Injury and Epilepsy: A Systematic Review to Identify Putative Biomarkers for Post-Traumatic EpilepsySemantic proximity Read ↗

A novel AAV9-dual microRNA-vector targeting GRIK2 in the hippocampus as a treatment for mesial temporal lobe epilepsySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.