Article
Paediatric non-progression following grandmother-to-child HIV transmission.
Retrovirology - 8 Sept 2016
Tsai M-H, Muenchhoff M, Adland E, Carlqvist A, Roider J, Cole D K, Sewell A K, Carlson J, Ndung'u T, Goulder P J R
Abstract excerpt
BACKGROUND: In contrast to adult HIV infection, where slow disease progression is strongly linked to immune control of HIV mediated by protective HLA class I molecules such as HLA-B*81:01, the mechanisms by which a minority of HIV-infected children maintain normal-for-age CD4 counts and remain clinically healthy appear to be HLA class I-independent and are largely unknown. To better understand these mechanisms,...
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