Article
Genome-wide analysis of chromosomal import patterns after natural transformation of Helicobacter pylori.
Nature communications - 22 Jun 2016
Bubendorfer Sebastian, Krebes Juliane, Yang Ines, Hage Elias, Schulz Thomas F, Bahlawane Christelle, Didelot Xavier, Suerbaum Sebastian
Abstract excerpt
Recombination plays a dominant role in the evolution of the bacterial pathogen Helicobacter pylori, but its dynamics remain incompletely understood. Here we use an in vitro transformation system combined with genome sequencing to study chromosomal integration patterns after natural transformation. A single transformation cycle results in up to 21 imports, and repeated transformations generate a maximum of 92...
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