Article
Bone marrow mesenchymal stem cells of the intrauterine growth-restricted rat offspring exhibit enhanced adipogenic phenotype.
International journal of obesity (2005) - 1 Nov 2016
Gong Ming, Antony Sahaya, Sakurai Reiko, Liu Jie, Iacovino Michelina, Rehan Virender K
Abstract excerpt
OBJECTIVE: Although intrauterine nutritional stress is known to result in offspring obesity and the metabolic phenotype, the underlying cellular/molecular mechanisms remain incompletely understood. We tested the hypothesis that compared with the controls, the bone marrow-derived mesenchymal stem cells (BMSCs) of the intrauterine growth-restricted (IUGR) offspring exhibit a more adipogenic phenotype. METHODS: A...
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