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Fetal Growth Restriction and Its Metabolism-Related Long-Term Outcomes—Underlying Mechanisms and Clinical Implications

31 Jan 2025

Abstract excerpt

The developmental origins of adult disease theory support the concept that undernourished fetuses are at risk of developing metabolic syndrome due to the energy-saving 'Thrifty Phenotype'. This metabolic plasticity represents an evolutionary adaptation that allows individuals to resist the intense pressure caused by cyclically recurring periods of nutritional deprivation. A comprehensive review was conducted...

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PMID: 39940412
DOI: 10.3390/nu17030555

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