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Article

The Drosophila melanogaster homolog of UBE3A is not imprinted in neurons.

Epigenetics - 1 Sept 2016

Hope Kevin A, LeDoux Mark S, Reiter Lawrence T

Abstract excerpt

In mammals, expression of UBE3A is epigenetically regulated in neurons and expression is restricted to the maternal copy of UBE3A. A recent report claimed that Drosophila melanogaster UBE3A homolog (Dube3a) is preferentially expressed from the maternal allele in fly brain, inferring an imprinting mechanism. However, complex epigenetic regulatory features of the mammalian imprinting center are not present in...

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Identifiers

PMID: 27599063
DOI: 10.1080/15592294.2016.1214783
PMCID: PMC5048722

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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