Article
Association between autoantibodies to the Arginine variant of the Zinc transporter 8 (ZnT8) and stimulated C-peptide levels in Danish children and adolescents with newly diagnosed type 1 diabetes.
Pediatric diabetes - 1 Sept 2012
Andersen Marie Louise M, Vaziri-Sani Fariba, Delli Ahmed, Pörksen Sven, Jacobssen Emma, Thomsen Jane, Svensson Jannet, Steen Petersen Jacob, Hansen Lars, Lernmark Ake, Mortensen Henrik B, Nielsen Lotte B
Abstract excerpt
BACKGROUND: The zinc transporter 8 (ZnT8) was recently identified as a common autoantigen in type 1 diabetes (T1D) and inclusion of ZnT8 autoantibodies (ZnT8Ab) was found to increase the diagnostic specificity of T1D. OBJECTIVES: The main aims were to determine whether ZnT8Ab vary during follow-up 1 year after diagnosis, and to relate the reactivity of three types of ZnT8Ab to the residual stimulated C-peptide...
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