Article
Effects of sleeve gastrectomy and rs9930506 FTO variants on angiopoietin/Tie-2 system in fat expansion and M1 macrophages recruitment in morbidly obese subjects.
Endocrine - 1 Dec 2016
Figueroa-Vega Nicté, Jordán Benjamín, Pérez-Luque Elva Leticia, Parra-Laporte Luis, Garnelo Serafín, Malacara Juan Manuel
Abstract excerpt
Angiogenesis in inflammation are hallmarks for adipose tissue expansion in obesity. The role of angiopoietin/Tie-2 system in adipose tissue expansion and immune cell recruitment is unclear. We studied the effect of sleeve gastrectomy and the influence of FTO rs9930506 polymorphism on Tie-2, angiopoietin-1 and angiopoietin-2 expression in morbid obesity. Fifteen morbidly obese subjects (4 men and 11 women) aged...
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