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Article

Fas and<i>FasL</i>Expression in Human Adipose Tissue Is Related to Obesity, Insulin Resistance, and Type 2 Diabetes

1 Nov 2013

Abstract excerpt

CONTEXT: Deletion of the death receptor Fas (CD95) in adipocytes of mice is associated with improved insulin sensitivity and reduced adipose tissue (AT) inflammation. OBJECTIVE: Here we investigate the relationship of AT Fas with human obesity. DESIGN AND METHODS: In paired samples of omental and sc AT from 256 lean and obese (including insulin-sensitive and insulin-resistant subgroups; n=60) participants, we...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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Identifiers

PMID: 24178789
DOI: 10.1210/jc.2013-2488

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