Article
Single Molecule Fluorescence Microscopy and Machine Learning for Rhesus D Antigen Classification.
Scientific reports - 1 Sept 2016
Borgmann Daniela M, Mayr Sandra, Polin Helene, Schaller Susanne, Dorfer Viktoria, Obritzberger Lisa, Endmayr Tanja, Gabriel Christian, Winkler Stephan M, Jacak Jaroslaw
Abstract excerpt
In transfusion medicine, the identification of the Rhesus D type is important to prevent anti-D immunisation in Rhesus D negative recipients. In particular, the detection of the very low expressed DEL phenotype is crucial and hence constitutes the bottleneck of standard immunohaematology. The current method of choice, adsorption-elution, does not provide unambiguous results. We have developed a complementary...
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