Article
A single-nucleotide polymorphism C-724 /del in the proter region of the apolipoprotein M gene is associated with type 2 diabetes mellitus.
Lipids in health and disease - 30 Aug 2016
Zhang Pu-Hong, Gao Jia-Lin, Pu Chun, Feng Gang, Wang Li-Zhuo, Huang Li-Zhu, Zhang Yao
Abstract excerpt
BACKGROUND: Apolipoprotein M (apoM) was the carrier of the biologically active lipid mediator sphingosine-1-phospate in high density lipoprotein cholesterol (HDL-C) and played a critical role in formation and maturation of prebeta-HDL-C particles. The plasma apoM levels were decreased obviously in patients with type 2 diabetes mellitus (T2DM). A new single-nucleotide polymorphism (SNP) C-724del in apoM promoter...
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