Article
Single nucleotide polymorphisms in the proximal promoter region of apolipoprotein M gene (apoM) confer the susceptibility to development of type 2 diabetes in Han Chinese.
Diabetes/metabolism research and reviews - 1 Jan 2007
Niu Nifang, Zhu Xilin, Liu Yang, Du Te, Wang Xin, Chen Dongmei, Sun Bei, Gu Harvest F, Liu Ying
Abstract excerpt
OBJECTIVE: Dyslipidemia correlating to insulin resistance is one of the key features in type 2 diabetes (T2D). Recent studies have demonstrated that apolipoprotein M (apoM) is important for the formation of prebeta-high-density lipoprotein (HDL) and cholesterol (CHO) efflux in macrophages to HDL. In the present study, we investigated the potential association of apoM genetic variation with the development of T2D....
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