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Article

A global map of genetic diversity in Babesia microti reveals strong population structure and identifies variants associated with clinical relapse.

Nature microbiology - 13 Jun 2016

Lemieux Jacob E, Tran Alice D, Freimark Lisa, Schaffner Stephen F, Goethert Heidi, Andersen Kristian G, Bazner Suzane, Li Amy, McGrath Graham, Sloan Lynne, Vannier Edouard, Milner Dan, Pritt Bobbi, Rosenberg Eric, Telford Sam, Bailey Jeffrey A, Sabeti Pardis C

Abstract excerpt

Human babesiosis caused by Babesia microti is an emerging tick-borne zoonosis of increasing importance due to its rising incidence and expanding geographic range(1). Infection with this organism, an intraerythrocytic parasite of the phylum Apicomplexa, causes a febrile syndrome similar to malaria(2). Relapsing disease is common among immunocompromised and asplenic individuals(3,4) and drug resistance has recently...

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PMID: 27572973
DOI: 10.1038/nmicrobiol.2016.79
PMCID: PMC5563076

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