Genomic analysis of local variation and recent evolution in Plasmodium vivax.

doi:10.1038/ng.3599

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Article

Genomic analysis of local variation and recent evolution in Plasmodium vivax.

Nature genetics - 1 Aug 2016

Pearson Richard D, Amato Roberto, Auburn Sarah, Miotto Olivo, Almagro-Garcia Jacob, Amaratunga Chanaki, Suon Seila, Mao Sivanna, Noviyanti Rintis, Trimarsanto Hidayat, Marfurt Jutta, Anstey Nicholas M, William Timothy, Boni Maciej F, Dolecek Christiane, Hien Tinh Tran, White Nicholas J, Michon Pascal, Siba Peter, Tavul Livingstone, Harrison Gabrielle, Barry Alyssa, Mueller Ivo, Ferreira Marcelo U, Karunaweera Nadira, Randrianarivelojosia Milijaona, Gao Qi, Hubbart Christina, Hart Lee, Jeffery Ben, Drury Eleanor, Mead Daniel, Kekre Mihir, Campino Susana, Manske Magnus, Cornelius Victoria J, MacInnis Bronwyn, Rockett Kirk A, Miles Alistair, Rayner Julian C, Fairhurst Rick M, Nosten Francois, Price Ric N, Kwiatkowski Dominic P

Abstract excerpt

The widespread distribution and relapsing nature of Plasmodium vivax infection present major challenges for the elimination of malaria. To characterize the genetic diversity of this parasite in individual infections and across the population, we performed deep genome sequencing of >200 clinical s...

Topics

Biological Evolution
Genetic Markers
Genetic Variation
Genomics
Humans
Malaria, Vivax
Plasmodium vivax

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PMID: 27348299
DOI: 10.1038/ng.3599
PMCID: PMC4966634

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-27348299-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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