Article

Microhaplotype deep sequencing assays to capture<i>Plasmodium vivax</i>infection lineages

2024-10-18

Abstract excerpt

The elimination of Plasmodium vivax is challenged by dormant liver stages (hypnozoites) that can reactivate months after initial infection resulting in relapses that enhance transmission. Relapsing infections confound antimalarial clinical efficacy trials due to the inability to distinguish between recurrences arising from blood-stage treatment failure (recrudescence), reinfection or relapse. Genetic relatedness o...

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Literature Corpus work: 9be46f17-9e48-50f7-afcb-e70ea10ce84b
DOI: 10.1101/2024.10.14.24315131

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