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Article

Association Between Single Nucleotide Polymorphisms in NFATC1 Signaling Pathway Genes and Susceptibility to Congenital Heart Disease in the Chinese Population.

Pediatric cardiology - 1 Dec 2016

Wang Fengyu, Wang Haili, Wang Lina, Zhou Shiyuan, Chang Mingxiu, Zhou Jiping, Dou Yongheng, Wang Yanli, Shi Xiangdong

Abstract excerpt

The nuclear factor of activated T lymphocytes (NFATC1) signaling has been demonstrated to play important roles in cardiac valve and septal development. Genetic variants in genes involved in NFATC1 signaling may affect their expression and promote the formation of congenital heart disease (CHD). The goal of this study was to investigate the associations of single nucleotide polymorphism (SNP) in seven genes...

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Source

Identifiers

PMID: 27567908
DOI: 10.1007/s00246-016-1469-5

Genes

NFATC1
FGFR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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