Article
Association of NFATc1 gene polymorphism with ventricular septal defect in the Chinese Han population.
Chinese medical journal - 1 Jan 2013
Shen Lei, Li Zhong-zhi, Shen A-dong, Liu Hui, Bai Song, Guo Jian, Yuan Feng, Li Xiao-feng
Abstract excerpt
BACKGROUND: Congenital heart disease (CHD) is a diverse group of diseases determined by genetic and environmental factors. Considerable research has been done on genes associated with the development of the heart. Recently, focus is on the role of transcription factor NFATc1 in the development of proper valve and septa. As part of a larger study, high density single nucleotide polymorphism (SNP) scanning was used...
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