Article
Analysis of Toll-like Receptor 9 Gene Polymorphisms in Sepsis.
In vivo (Athens, Greece) - 1 Jan 2000
Atalan Nazan, Karagedik Hande, Acar Leyla, Isbir Selim, Yilmaz Seda Gulec, Ergen Arzu, Isbir Turgay
Abstract excerpt
AIM: To analyze the effect of TLR-9 (-1486 T>C) and TLR-9 (C>T) gene polymorphisms both at TLR-9 levels and together with their sepsis parameters. In this regard, the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technique was used in order to detect TLR-9 gene polymorphisms, whereas the ELISA technique was used to analyze TLR-9 serum levels in 80 sepsis patients and 100 healthy...
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