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Article

miR-378 attenuates muscle regeneration by delaying satellite cell activation and differentiation in mice

26 Aug 2016

Abstract excerpt

Skeletal muscle mass and homeostasis during postnatal muscle development and regeneration largely depend on adult muscle stem cells (satellite cells). We recently showed that global overexpression of miR-378 significantly reduced skeletal muscle mass in mice. In the current study, we used miR-378 transgenic (Tg) mice to assess the in vivo functional effects of miR-378 on skeletal muscle growth and regeneration....

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PMID: 27563005
DOI: 10.1093/abbs/gmw077

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