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Article

Distinct clinicopathological features of NAB2-STAT6 fusion gene variants in solitary fibrous tumor with emphasis on the acquisition of highly malignant potential.

Human pathology - 1 Mar 2015

Akaike Keisuke, Kurisaki-Arakawa Aiko, Hara Kieko, Suehara Yoshiyuki, Takagi Tatsuya, Mitani Keiko, Kaneko Kazuo, Yao Takashi, Saito Tsuyoshi

Abstract excerpt

The impact of NGFI-A binding protein 2 (NAB2)-signal transducer and activator of transcription 6 (STAT6) fusion on the biological behavior and the mechanism of acquisition of malignant phenotype in solitary fibrous tumor (SFT) is not well understood. We examined variations of the NAB2-STAT6 fusion gene in 40 cases of SFT using formalin-fixed, paraffin-embedded tissues and secondary genetic alterations of tumor...

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Source

Identifiers

PMID: 25582503
DOI: 10.1016/j.humpath.2014.11.018

Genes

STAT6
NAB2
TERT
PDGFRB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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