Article
Polyanionic carbosilane dendrimers prevent hepatitis C virus infection in cell culture.
Nanomedicine : nanotechnology, biology, and medicine - 1 Jan 2017
Sepúlveda-Crespo Daniel, Jiménez José Luis, Gómez Rafael, De La Mata Francisco Javier, Majano Pedro L, Muñoz-Fernández Ma Ángeles, Gastaminza Pablo
Abstract excerpt
Hepatitis C virus (HCV) infection is a major biomedical problem worldwide. Although new direct antiviral agents (DAAs) have been developed for the treatment of chronic HCV infection, the potential emergence of resistant virus variants and the difficulties to implement their administration worldwide make the development of novel antiviral agents an urgent need. Moreover, no effective vaccine is available against...
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