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Article

Antiviral Activity of Chitosan Nanoparticles Encapsulating Curcumin Against Hepatitis C Virus Genotype 4a in Human Hepatoma Cell Lines.

International journal of nanomedicine - 1 Jan 2020

Loutfy Samah A, Elberry Mostafa H, Farroh Khaled Yehia, Mohamed Hossam Taha, Mohamed Aya A, Mohamed ElChaimaa B, Faraag Ahmed Hassan Ibrahim, Mousa Shaker A

Abstract excerpt

PURPOSE: Current direct-acting antiviral agents for treatment of hepatitis C virus genotype 4a (HCV-4a) have been reported to cause adverse effects, and therefore less toxic antivirals are needed. This study investigated the role of curcumin chitosan (CuCs) nanocomposite as a potential anti-HCV-4a agent in human hepatoma cells Huh7. METHODS: Docking of curcumin and CuCs nanocomposite and binding energy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32368050
DOI: 10.2147/IJN.S241702
PMCID: PMC7184126

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