Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Contribution of CD8+ T cells to inflammatory cytokine production in systemic sclerosis (SSc).

Autoimmunity - 1 Dec 2016

Klein Matthias, Schmalzing Marc, Almanzar Giovanni, Benoit Sandrine, Hamm Henning, Tony Hans-Peter, Goebeler Matthias, Prelog Martina

Abstract excerpt

Only limited attention has been paid to the role of CD8 + T cells in the etiopathogenesis and progression of systemic sclerosis (SSc). CD8 + T cells may have autoantigen-specific and pro-inflammatory but also immunomodulatory properties. To investigate the differentiation of CD8 + T cells, staining of cell surface factors and of chemokine receptors were performed. In addition, the cytokine-producing ability of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoantibodies
Share to CD8-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunophenotyping

Share to Inflammation Mediators

Share to Lymphocyte Count

Share to Receptors, Chemokine

Share to Scleroderma, Systemic

Share to T-Lymphocyte Subsets

Source

Identifiers

PMID: 27560622
DOI: 10.1080/08916934.2016.1217997

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Contribution of CD8+ T cells to inflammatory cytokine production in systemic sclerosis (SSc).PMID 27560622Read ↗

Alterations in peripheral T- and B-cell subsets in patients with systemic sclerosis.Semantic proximity Read ↗

Distinct immune profiles characterize patients with diffuse or limited systemic sclerosis.Semantic proximity Read ↗

The pronounced Th17 profile in systemic sclerosis (SSc) together with intracellular expression of TGFbeta and IFNgamma distinguishes SSc phenotypes.Semantic proximity Read ↗

CD4+ Group 1 Innate Lymphoid Cells (ILC) Form a Functionally Distinct ILC Subset That Is Increased in Systemic SclerosisSemantic proximity Read ↗

Circulating γ/δ T cells in systemic sclerosis exhibit activated phenotype and enhance gene expression of proalpha2(I) collagen of fibroblasts.Semantic proximity Read ↗

Disease Manifestation and Inflammatory Activity as Modulators of Th17/Treg Balance and RORC/FoxP3 Methylation in Systemic SclerosisSemantic proximity Read ↗

CD4+ and CD8+ subsets: naive and memory cells in the peripheral blood of patients with systemic sclerosis.Semantic proximity Read ↗

Skin-Resident Effector Memory CD8+CD28- T Cells Exhibit a Profibrotic Phenotype in Patients with Systemic Sclerosis.Semantic proximity Read ↗

T cells of patients with systemic sclerosis or Sjögren's disease display an aberrant metabolic state and memory phenotype in blood and lungs.Semantic proximity Read ↗

Lymphocyte subset abnormalities in early severe scleroderma favor a Th2 phenotype and are not altered by prior immunosuppressive therapy.Semantic proximity Read ↗

Phenotype markers and cytokine intracellular production by CD8+ gammadelta T lymphocytes do not support a regulatory T profile in Behçet's disease patients and healthy controls.Semantic proximity Read ↗

Association of immunological cell profiles with specific clinical phenotypes of scleroderma disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.