Article
Distinct immune profiles characterize patients with diffuse or limited systemic sclerosis.
Clinical immunology (Orlando, Fla.) - 1 Jul 2003
Ingegnoli Francesca, Trabattoni Daria, Saresella Marina, Fantini Flavio, Clerici Mario
Abstract excerpt
Mitogen-stimulated IL-2, IFN-gamma, TNF-alpha (type 1 cytokines), and IL-10 (type 2 cytokine) production by peripheral blood mononuclear cells, as well as expression of surface markers on immune cells, was evaluated in systemic sclerosis (SSc) patients. Fifty-four SSc patients with either diffuse (dSSc) or limited (lSSc) disease and 20 age- and sex-matched healthy controls (HCs) were examined. Fourteen patients...
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