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Article

Integrative analysis of somatic mutations and transcriptomic data to functionally stratify breast cancer patients.

BMC genomics - 22 Aug 2016

Zhang Jie, Abrams Zachary, Parvin Jeffrey D, Huang Kun

Abstract excerpt

BACKGROUND: Somatic mutations can be used as potential biomarkers for subtyping and predicting outcomes for cancer patients. However, cancer patients often carry many somatic mutations, which do not always concentrate on specific genomic loci, suggesting that the mutations may affect common pathways or gene interaction networks instead of common genes. The challenge is thus to identify the...

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Identifiers

PMID: 27556157
DOI: 10.1186/s12864-016-2902-0
PMCID: PMC5001235

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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